Biological Basis of Cold and Heat Pattern of Rheumatoid Arthritis in Traditional Chinese Medicine

An integrative mode of the disease classification in Western medicine and the syndrome differentiation in Chinese medicine is already the chief mode of sorting applied in clinical practice of Chinese medicine and integrative medicine. In this study, the cold and heat pattern of rheumatoid arthritis were comparatively analyzed. A range of facts, including the correlation of syndrome differentiations and therapeutic effects, the difference of laboratorial examination and omics expression between cold and heat pattern of RA were reviewed to demonstrate the biological basis of RA syndrome differentiations. It indicates that the better knowledge of the biological basis involved in syndrome differentiations of Chinese medicine might help to choose the most appropriate treatment.