Methodology for Determining the Quantity of Major Components in Herbal Complex by LC/MS

ObjectiveThis article aims to study the total elements of Chinese complex, YL2000, by LC-MS.MethodsThe total flavonoids, total alkaloids, and total coumarins in YL2000 are determined based on the chemical structure (analogue) and using the standard compounds as a reference.ResultsThe quantity of the three elements is similar to the quantity produced by UV test.ConclusionsThis is the first attempt to determine the total quantity of the elements in herbal complex, which is helpful for the element quality control in Chinese medical complex.