Albendazole causes stage-dependent developmental toxicity and is deactivated by a mammalian metabolization system in a modified zebrafish embryotoxicity test

► The zebrafish embryo toxicity test with an external metabolization system was further developed and additional testing time points with extended exposure durations were included. ► The anthelmintic drug albendazole caused stage dependent toxic effects in zebrafish embryos. ► Albendazole was efficiently metabolized and deactivated by the external metabolization system.