کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
2594739 1132277 2011 4 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Perinatal exposure of rats to Bisphenol A affects fertility of male offspring—An overview
موضوعات مرتبط
علوم زیستی و بیوفناوری علوم محیط زیست بهداشت، سم شناسی و جهش زایی
پیش نمایش صفحه اول مقاله
Perinatal exposure of rats to Bisphenol A affects fertility of male offspring—An overview
چکیده انگلیسی

Endocrine disruptors (ED) induce both functional and behavioral reproductive abnormalities. Bisphenol A (BPA) is a known ED that leaches from polycarbonate plastics, as such human exposure is common. Maternal BPA exposure has been shown to have negative effects on the fertility of male offspring. Pregnant rats exposed perinatally to environmentally relevant doses of BPA gave birth to offspring with significantly impaired spermatogenesis and fertility. Perinatal exposure had deleterious effects on the male germ line which manifested as impairments in the fertility of F1 male offspring and subsequent F2 and F3 generations. This overview is an attempt to summarize the currently available data in the literature with regards to perinatal BPA exposure and male fertility.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Reproductive Toxicology - Volume 31, Issue 3, April 2011, Pages 359–362
نویسندگان
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