کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
2599974 1133244 2012 4 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
3,4-Methylenedioxypyrovalerone (MDPV): Chemistry, pharmacology and toxicology of a new designer drug of abuse marketed online
موضوعات مرتبط
علوم زیستی و بیوفناوری علوم محیط زیست بهداشت، سم شناسی و جهش زایی
پیش نمایش صفحه اول مقاله
3,4-Methylenedioxypyrovalerone (MDPV): Chemistry, pharmacology and toxicology of a new designer drug of abuse marketed online
چکیده انگلیسی

The illicit marketplace of substances of abuse continually offers for sale legal alternatives to controlled drugs to a large public. In recent years, a new group of designer drugs, the synthetic cathinones, has emerged as a new trend, particularly among young people. The 3,4-methylenedioxypyrovalerone (MDPV), one of this synthetic compounds, caused an international alert for its cardiovascular and neurological toxicity. This substance, sold as bath salts, has caused many serious intoxications and some deaths in several countries. The aim of this paper is summarise the clinical, pharmacological and toxicological information about this new designer drug.


► 3,4-Methylenedioxypyrovalerone (MDPV) is a new designer drug of abuse.
► This substance is marketed as bath salts.
► MDPV is used as alternative to other illicit stimulants.
► MDPV can produce neurological and cardiovascular toxicity.
► Literature data suggest a high risk of acute toxicity, tolerance and dependence.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Toxicology Letters - Volume 208, Issue 1, 5 January 2012, Pages 12–15
نویسندگان
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