Intérêt et limites des biomarqueurs en médecine d'urgence

The use of biomarkers has resulted in a dramatic improvement in cardiovascular, respiratory and sepsis diagnosis performance. Highly performing bioassays are used to identify an increase in biomarker concentrations, which sensitivity and specificity remains to be carefully assessed in the setting of emergency. New management strategies have been elaborated based on the values of biomarkers. Although supportive for several important emergency diagnoses, biomarkers have some limitations that have to be known.