|کد مقاله||کد نشریه||سال انتشار||مقاله انگلیسی||ترجمه فارسی||نسخه تمام متن|
|26341||43948||2016||6 صفحه PDF||سفارش دهید||دانلود رایگان|
• N-Acryloyl amino acid esters and peptides can be utilized as radical acceptors in the PET induced decarboxylation reaction.
• The photoreaction afforded modified amino acids and peptides under mild reaction conditions.
• This methodology can provide decarboxylated coupling peptides containing γ-amino acids.
The photoinduced electron transfer (PET) promoted decarboxylative radical additions of carboxylic acids using N-acryloyl amino acid esters and peptides as radical acceptors smoothly afforded the corresponding modified amino acids and peptides under mild reaction conditions. The radical additions of α-amino acids led to the formation of γ- and α-dipeptide, and peptides underwent peptide coupling via decarboxylation.
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Journal: Journal of Photochemistry and Photobiology A: Chemistry - Volume 317, 15 February 2016, Pages 50–55