کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
2637378 1563495 2013 5 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Extended-spectrum β-lactamase-producing Enterobacteriaceae in healthy companion animals living in nursing homes and in the community
موضوعات مرتبط
علوم زیستی و بیوفناوری ایمنی شناسی و میکروب شناسی میکروب شناسی
پیش نمایش صفحه اول مقاله
Extended-spectrum β-lactamase-producing Enterobacteriaceae in healthy companion animals living in nursing homes and in the community
چکیده انگلیسی

BackgroundAnimals could be reservoirs of extended-spectrum β-lactamases (ESBL) strains, but epidemiologic data on ESBL-producing bacteria in healthy pets are missing. We determined the prevalence of ESBL-producing Enterobacteriaceae in pets living in nursing homes and in households to investigate the potential role of companion animals as carriers of ESBL.MethodsThree hundred seventy-six rectal swabs were taken from cats and dogs visiting or living in 68 randomly selected nursing homes or brought to 26 veterinary practices in Switzerland for routine mandatory vaccination. Isolates were identified by matrix-assisted laser desorption ionization time of flight mass spectrometry. Confirmatory tests were performed on the isolated Enterobacteriaceae. Phenotypic ESBL isolates were investigated for genetic determinants of resistance.ResultsThe overall prevalence of ESBL isolates, adjusted for clustering, was 2.5% (95% confidence interval: 1.3-4.6). Pets that received an antibiotic treatment in the 3 months prior to the study had a higher risk to be carriers of these microorganisms (Adjusted odds ratio, 7.8; 95% confidence interval: 2.2-26.9).ConclusionESBL-producing Enterobacteriaceae were present in healthy cats and dogs, particularly from those with a history of antibiotic treatment. These animals could become ESBL reservoirs. Investigations are needed to assess the possible transmission of these microorganisms between pets and humans.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: American Journal of Infection Control - Volume 41, Issue 9, September 2013, Pages 831–835
نویسندگان
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