کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
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2797185 | 1155637 | 2012 | 7 صفحه PDF | دانلود رایگان |
Background and aimsIn this study, broccoli sprout powder (BSP), a good source of bioactive components, was used as supplementary treatment in type 2 diabetic patients.MethodsThis randomized clinical trial included 81 patients with type 2 diabetes. Participants were randomly assigned to consume 10 g/d BSP (group A), 5 g/d BSP (group B), or the placebo (group C), each for 4 weeks. Fasting blood glucose (FBS), total cholesterol (TC), triglyceride concentration (TG), LDL-C, HDL-C, and oxidized-LDL were measured at baseline and 4 weeks after treatment. The ratios of OX-LDL/LDL, atherogenic index of plasma (AIP; log TG/HDL), TC/HDL and LDL/HDL were calculated as cardiovascular risk factors parameters, at baseline and 4 weeks after treatment.ResultsSeventy-two patients completed the study; n = 23, 26 and 23 for groups A, B and C, respectively. After 4 weeks, BSP in dose of 10 g/d, significantly decreased serum triglycerides, OX-LDL/LDL ratio and AIP (p < 0.05 for treatment effect). HDL-C concentration was significantly higher (p < 0.01 for treatment) in group A as compared with group B and placebo.ConclusionsBSP as supplementary treatment in type 2 diabetes could have favorable effects on lipid profiles and OX-LDL/LDL ratio, as risk factors for cardiovascular disease.
Journal: Diabetes Research and Clinical Practice - Volume 96, Issue 3, June 2012, Pages 348–354