کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
2798605 1155692 2007 6 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Incidence of critical limb ischemia and amputation outcome in contralateral limb in diabetic patients hospitalized for unilateral critical limb ischemia during 1999–2003 and followed-up until 2005
موضوعات مرتبط
علوم زیستی و بیوفناوری بیوشیمی، ژنتیک و زیست شناسی مولکولی علوم غدد
پیش نمایش صفحه اول مقاله
Incidence of critical limb ischemia and amputation outcome in contralateral limb in diabetic patients hospitalized for unilateral critical limb ischemia during 1999–2003 and followed-up until 2005
چکیده انگلیسی

We studied the incidence of critical limb ischemia (CLI) and amputation outcome of the contralateral limb in 533 diabetic patients hospitalized in our diabetic foot centre because of CLI from 1999 to 2003 and followed-up until 2005.The cumulative incidence rate during the 6-year period reached 49.8% (CI confidence interval = 40.6–59.6). All patients underwent arteriography and in 181 (98.4%) the revascularization was performed without different feasibility (p = 0.077) compared to that (95.3%) in the initial patients. The severity of lesion evaluated with Wagner grade was lower (χ2 = 33.5, p < 0.001) and also the frequency of midfoot and above-the-ankle amputations was lower (p < 0.001 and p = 0.022, respectively) in contralateral patients. There was no evidence from the logistic analysis to support the association between any of the investigated variables and incidence of CLI in the contralateral limb.Over a 6-year period, almost 50% of the diabetic patients with unilateral CLI developed a CLI in the contralateral limb: however, both severity of foot lesion and amputation level was significantly lower. This fact can be due to prompt therapeutic interventions, made possible thanks to an increased patient awareness acquired by training during the treatment of the unilateral limb.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Diabetes Research and Clinical Practice - Volume 77, Issue 3, September 2007, Pages 445–450
نویسندگان
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