کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
28235 44066 2007 6 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Polycyclic compounds by sunlight exposure of the drug rosuvastatin in water
موضوعات مرتبط
مهندسی و علوم پایه مهندسی شیمی بیو مهندسی (مهندسی زیستی)
پیش نمایش صفحه اول مقاله
Polycyclic compounds by sunlight exposure of the drug rosuvastatin in water
چکیده انگلیسی

Irradiation of rosuvastatin in water by sunlight or UV lamp (Pyrex) affords cyclic compounds. The main photo-induced reaction is cyclization of the drug to give diastereomeric dihydrobenzoquinazolines. Products derived from side-chain loss were also isolated in the irradiation mixture, and characterized as dihydrobenzoquinazoline and benzoquinazoline derivatives by spectroscopic means. Photoproducts structure elucidation and mechanistic hypothesis are reported.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Photochemistry and Photobiology A: Chemistry - Volume 187, Issues 2–3, 15 April 2007, Pages 263–268
نویسندگان
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