Expresión de COX-2 en arterias y células vasculares de pacientes diabéticos y no diabéticos

COX-2 expression in internal mammary arteries is related to type 2 diabetes and a poorer EuroSCORE. In addition, COX-2 expression was experimentally increased when cells from nondiabetic patients were incubated with triglycerides, which enhances the associations among hypertriglyceridemia, type 2 diabetes, vascular inflammation, and a poorer clinical prognosis.