کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
2864938 1573215 2008 6 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Digoxin: Current Use and Approach to Toxicity
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی کاردیولوژی و پزشکی قلب و عروق
پیش نمایش صفحه اول مقاله
Digoxin: Current Use and Approach to Toxicity
چکیده انگلیسی
Heralded as the oldest known cardiovascular drug, digoxin remains widely used today in the face of increasing rates in heart failure and atrial fibrillation despite the emergence of newer medications. Its hemodynamic, neurohormonal and electrophysiologic actions make it a suitable adjunctive, evidence-based therapy for the above conditions. Its narrow therapeutic index and its toxicity, however, have become more relevant as aging, comorbid diseases, and polypharmacy make more patients vulnerable. Because signs and symptoms of digoxin toxicity are mostly nonspecific, a high index of suspicion is crucial for early recognition and appropriate management.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: The American Journal of the Medical Sciences - Volume 336, Issue 5, November 2008, Pages 423-428
نویسندگان
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