کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
2894298 | 1172430 | 2007 | 7 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Residual platelet reactivity is associated with clinical and laboratory characteristics in patients with ischemic heart disease undergoing PCI on dual antiplatelet therapy
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کلمات کلیدی
موضوعات مرتبط
علوم پزشکی و سلامت
پزشکی و دندانپزشکی
کاردیولوژی و پزشکی قلب و عروق
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چکیده انگلیسی
In patients with acute coronary syndromes and elective PCI diabetes is independently associated with RPR [group A: OR = 2.9 (1.5-5.7) by 10 μM ADP, OR = 5.3 (1.1-27.8) by PFA-100; group B: OR = 4.0 (1.6-10.0) by 10 μM ADP]; reduced left ventricular systolic function [OR = 3.7 (2.2-6.5) by AA-PA, OR = 2.7 (1.6-4.6) by PFA-100], chronic use of aspirin [OR = 0.2 (0.1-0.4) by AA-PA, OR = 0.3 (0.2-0.5) by PFA-100] and loading dose of clopidogrel [OR = 0.2 (0.06-0.5) by 10 μM ADP] were independent variables significantly associated with RPR in patients undergoing elective PCI. In addition, inflammatory status was found to be significantly associated with RPR in both groups of patients. These results provide indications for the selection of patients for whom the evaluation of platelet reactivity could be useful.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Atherosclerosis - Volume 195, Issue 1, November 2007, Pages e217-e223
Journal: Atherosclerosis - Volume 195, Issue 1, November 2007, Pages e217-e223
نویسندگان
Rossella Marcucci, Anna Maria Gori, Rita Paniccia, Cristina Giglioli, Piergiovanni Buonamici, David Antoniucci, Gian Franco Gensini, Rosanna Abbate,