Relación entre hipertensión arterial y la demencia

The prevalence of high blood pressure and dementia disorders is high. The number of patients is expected to increase in the near future, especially for dementias and associated to the population aging. As there are currently no curative treatments, effective prevention is needed. Cross-sectional, and especially population, studies, have showed a relation between high blood pressure and cognitive decline and dementia, this not being only limited to vascular dementia but also includes Alzheimer's disease. However, intervention studies have failed to change the presence of cognitive deterioration in the groups studied. In this work, and through a review of the literature, we have posed the questions on what mechanisms would related high blood pressure with a degenerative neuron disease, such as Alzheimer's disease, and why interventional studies have not achieved a reduction in the incidence of dementia of the patients treated.