کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
29274 44143 2007 8 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Irradiation of fluvastatin in water: Structure elucidation of photoproducts
موضوعات مرتبط
مهندسی و علوم پایه مهندسی شیمی بیو مهندسی (مهندسی زیستی)
پیش نمایش صفحه اول مقاله
Irradiation of fluvastatin in water: Structure elucidation of photoproducts
چکیده انگلیسی

Fluvastatin is easily transformed in water by solar irradiation. One day-light exposure induces a complete degradation of the drug and formation of a mixture of products. Different chromatographic processes led to the isolation of dihydrobenzocarbazole, benzocarbazole, azonane-2,7-dione and spiro[4.4]azononane derivatives. Structures of photoproducts were elucidated by spectroscopic means. Photocyclization and photooxygenation are the main reactions involved in the formation of the observed products.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Photochemistry and Photobiology A: Chemistry - Volume 189, Issues 2–3, 25 June 2007, Pages 264–271
نویسندگان
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