کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
2957293 1578079 2010 14 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
A review of endothelial dysfunction in diabetes: a focus on the contribution of a dysfunctional eNOS
موضوعات مرتبط
علوم زیستی و بیوفناوری علم عصب شناسی سیستم های درون ریز و اتونومیک
پیش نمایش صفحه اول مقاله
A review of endothelial dysfunction in diabetes: a focus on the contribution of a dysfunctional eNOS
چکیده انگلیسی

Although the etiology of vascular dysfunction in diabetes has been extensively investigated in both humans as well as animal models of human diabetes, the relative importance of the cellular pathways involved is still not fully understood. In this review, we focus on reviewing the literature that provides insights into how an acute exposure to hyperglycemia results in a dysregulation of endothelial nitric oxide synthase function, the subsequent downstream effects of endothelial nitric oxide synthase dysregulation, and the development of endothelial dysfunction.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of the American Society of Hypertension - Volume 4, Issue 3, May–June 2010, Pages 102–115
نویسندگان
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