Treatment of electrical storms in Brugada syndrome

Patients with Brugada syndrome (BrS) not uncommonly suffer from recurrent and recalcitrant ventricular fibrillation episodes, the so-called “electrical storm” which is malignant and potentially lethal event. While electrical storm in BrS is a therapeutic challenge, fortunately there are effective therapeutic solutions which must be compulsory applied: Elimination of precipitating factors, isoproterenol and oral quinidine are the first 2 therapeutic steps that one must urgently commenced. And if this measure should fail, ablation of the triggering ventricular premature beats and/or substrate ablation at the anterior aspect of the right ventricular outflow tract should be performed.