کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
2999887 | 1180308 | 2011 | 7 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
The Science and Ethics of Induced Pluripotency: What Will Become of Embryonic Stem Cells?
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کلمات کلیدی
MSCICMUCBSCNTNBACiPS - IPSSomatic cell nuclear transfer - انتقال هسته سلول سوماتیHES - او هستhuman embryonic stem - بذر جنین انسانInner cell mass - توده سلولی داخلیUmbilical cord blood - خون بند نافembryonic stem - ساقه جنینinduced pluripotent stem - ساقه پلورپوفنت القا شده استMesenchymal stem cell - سلول های بنیادی مزانشیمیIn vitro fertilization - لقاح در خارج از بدن یا آیویافIVF - لقاح مصنوعی
موضوعات مرتبط
علوم پزشکی و سلامت
پزشکی و دندانپزشکی
کاردیولوژی و پزشکی قلب و عروق
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: The Science and Ethics of Induced Pluripotency: What Will Become of Embryonic Stem Cells? The Science and Ethics of Induced Pluripotency: What Will Become of Embryonic Stem Cells?](/preview/png/2999887.png)
چکیده انگلیسی
For over a decade, the field of stem cell research has advanced tremendously and gained new attention in light of novel insights and emerging developments for regenerative medicine. Invariably, multiple considerations come into play, and clinicians and researchers must weigh the benefits of certain stem cell platforms against the costs they incur. Notably, human embryonic stem (hES) cell research has been a source of continued debate, leading to differing policies and regulations worldwide. This article briefly reviews current stem cell platforms, looking specifically at the two existing pluripotent lines available for potential therapeutic applications: hES cells and induced pluripotent stem (iPS) cells. We submit iPS technology as a viable and possibly superior alternative for future medical and research endeavors as it obviates many ethical and resource-related concerns posed by hES cells while prospectively matching their potential for scientific use. However, while the clinical realities of iPS cells appear promising, we must recognize the current limitations of this technology, avoid hype, and articulate ethically acceptable medical and scientific goals.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Mayo Clinic Proceedings - Volume 86, Issue 7, July 2011, Pages 634-640
Journal: Mayo Clinic Proceedings - Volume 86, Issue 7, July 2011, Pages 634-640
نویسندگان
David G. BA, Timothy J. MD, PhD, Paul S. MD, MPH, C. Christopher MD,