کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
3000265 | 1180324 | 2008 | 7 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Human Papillomavirus and Vaccination
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کلمات کلیدی
PAPQALYVLPRRPPapanicolaouCervical intraepithelial neoplasia - neoplasia intraepithelial گردن رحمCin - جینQuality-adjusted life-year - طول عمر سال تنظیم شده با کیفیتconfidence interval - فاصله اطمینانHuman papillomavirus - ویروس پاپیلوم انسانیHPV - ویروس پایپلوم انسانیRecurrent respiratory papillomatosis - پاپیلوماتوز مجدد تنفسی
موضوعات مرتبط
علوم پزشکی و سلامت
پزشکی و دندانپزشکی
کاردیولوژی و پزشکی قلب و عروق
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چکیده انگلیسی
Human papillomavirus (HPV) infection is the most common sexually transmitted infection in the United States. Modeling estimates suggest that more than 80% of sexually active women will have acquired genital HPV by age 50 years. Although most infections are transient and asymptomatic, persistent infection with high-risk types of HPV can lead to precancerous lesions and progress to cancer. In June 2006, the US Food and Drug Administration licensed the first vaccine to prevent cervical cancers and other diseases in women. This quadrivalent vaccine protects against HPV-6, HPV-11, HPV-16, and HPV-18, which are responsible for 70% of cervical cancers and 90% of genital warts. Several studies have been published examining the vaccine's efficacy, duration, immunogenicity, and safety. Questions and controversy remain regarding mandatory vaccination, need for booster doses, and cost-effectiveness.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Mayo Clinic Proceedings - Volume 83, Issue 6, June 2008, Pages 701-707
Journal: Mayo Clinic Proceedings - Volume 83, Issue 6, June 2008, Pages 701-707
نویسندگان
Christine M. MD,