کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
3039945 1579691 2015 5 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Preoperative C-reactive protein predicts the need for repeated intracerebral brain abscess drainage
موضوعات مرتبط
علوم زیستی و بیوفناوری علم عصب شناسی عصب شناسی
پیش نمایش صفحه اول مقاله
Preoperative C-reactive protein predicts the need for repeated intracerebral brain abscess drainage
چکیده انگلیسی


• Patients with brain abscesses might require more than one draining procedure.
• High preOP CRP was associated with repeated draining procedures.
• Elevated CRP at admission suggests closer clinical and radiological follow-up.

BackgroundTo determine predicting factors for repeated surgical drainage in patients with intracerebral brain abscesses.MethodsPatients operated between 01/2008 and 10/2013 with a single-burr-hole technique to drain an intracerebral brain abscess were included from our prospective database. Clinical and radiological characteristics were analyzed retrospectively and compared between patients requiring a single surgical abscess drainage (S group) vs. patients requiring multiple surgical abscess aspirations (M group).ResultsThirty-five patients (mean age 42.6 years, 14 females) including 27 patients in the S group and 8 in the M group were included in this study. Age, gender, causing bacterial agent, surgical technique and abscess volume were comparable for both groups. Preoperative mean C-reactive protein (CRP) (13.9 mg/l vs. 56.1 mg/l, p = 0.015) was significantly higher in the M group. Preoperative mean leukocyte count (12.3 × 109/l vs. 8.9 × 109/l, p = 0.050) was borderline significantly higher in the M group. Although the origin in the overall population was cryptogenic in 43% of the cases, this was never the case in the patient population needing multiple surgeries.DiscussionPatients with multiple intracerebral brain abscess aspirations showed significantly higher preoperative CRP values than patients who needed surgery only once. Patients with high CRP values at admission and obvious origin of infection might need closer radiographic as well as clinical and laboratory exams after surgery to earlier select patients, which need repeated surgery.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Clinical Neurology and Neurosurgery - Volume 131, April 2015, Pages 26–30
نویسندگان
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