کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
3040157 1579699 2014 8 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Chemoprophylaxis for venous thromboembolism in traumatic brain injury: A review and evidence-based protocol
موضوعات مرتبط
علوم زیستی و بیوفناوری علم عصب شناسی عصب شناسی
پیش نمایش صفحه اول مقاله
Chemoprophylaxis for venous thromboembolism in traumatic brain injury: A review and evidence-based protocol
چکیده انگلیسی

Venous thromboembolism (VTE) is a recognized source of morbidity and mortality in patients suffering traumatic brain injury (TBI). While traumatic brain injury is a recognized risk factor for the development of VTE, its presence complicates the decision to begin anticoagulation due to fear of exacerbating the intracranial hemorrhagic injury. The role of chemoprophylaxis in this setting is poorly defined, leading to a wide variability in clinical practice. A comprehensive review of the literature was performed in an effort to summarize relevant data and construct a chemoprophylaxis protocol to be implemented in a Level I Trauma Center. The review reveals robust evidence regarding the safety and efficacy of chemoprophylaxis in the setting of TBI following demonstration of a stable intracranial injury. In light of this data, a protocol is assembled that, in the absence of predetermined exclusion criteria, will initiate chemoprophylaxis within 24 h after the demonstration of a stable intracranial injury by computed tomography (CT).

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Clinical Neurology and Neurosurgery - Volume 123, August 2014, Pages 109–116
نویسندگان
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