کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
3040204 1579697 2014 6 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Patent foramen ovale and asymptomatic brain lesions in military fighter pilots
موضوعات مرتبط
علوم زیستی و بیوفناوری علم عصب شناسی عصب شناسی
پیش نمایش صفحه اول مقاله
Patent foramen ovale and asymptomatic brain lesions in military fighter pilots
چکیده انگلیسی

Background and purposePrevious studies have reported higher incidence of white matter lesions (WMLs) in military pilots. The anti-gravity straining maneuver, which fighter military pilots perform numerously during a flight is identical to the valsalva maneuver. We sought to investigate the prevalence of right-to-left shunt (RLS) associated with WMLs in military pilots.MethodsA prospective study was performed involving military pilots who visited the Airomedical Center. The pilots underwent brain magnetic resonance imaging (MRI) scan and transcranial Doppler (TCD) with intravenous injection of agitated saline solution for the detection of RLS. Periventricular WMLs (PVWMLs) on MRI were graded using Fazeka's scale, and deep WMLs (DWMLs) were graded using Scheltens's scale.ResultsThis study included 81 military pilots. RLS on TCD was observed less frequently in non-fighter pilots than in fighter pilots (35.5% vs. 64.5%, p = 0.011). Fighter pilot was an independently associated factor with RLS on the TCD. DWMLs were independently associated with RLSs through a patent foramen ovale (PFO) (OR 3.507, 95% CI 1.223–10.055, p = 0.02).ConclusionThe results suggest that DWMLs in military pilots may significantly be associated with RLS via PFO. Additional investigations are warranted.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Clinical Neurology and Neurosurgery - Volume 125, October 2014, Pages 9–14
نویسندگان
, , , , , ,