کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
3049635 1579854 2014 5 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Validation of the Generalized Anxiety Disorder-7 in people with epilepsy: A MEPSY study
موضوعات مرتبط
علوم زیستی و بیوفناوری علم عصب شناسی علوم اعصاب رفتاری
پیش نمایش صفحه اول مقاله
Validation of the Generalized Anxiety Disorder-7 in people with epilepsy: A MEPSY study
چکیده انگلیسی


• The Generalized Anxiety Disorder-7 (GAD-7) is a tool for screening GAD.
• We validated the GAD-7 on the detection of anxiety in Korean patients with epilepsy.
• At a cutoff score of 6, the GAD-7 had a sensitivity of 92.2% and a specificity of 89.1%.
• The GAD-7 is a reliable and valid screening tool for detecting GAD in epilepsy.

The Generalized Anxiety Disorder-7 (GAD-7) is a valuable instrument to screen for anxiety in primary care patients. However, it has not been validated in people with epilepsy (PWE). Therefore, we validated the GAD-7 and examined its differential effect from adverse effects of antiepileptic drugs (AEDs) on the detection of anxiety in Korean PWE. Eligible patients who visited outpatient clinics in 4 tertiary care hospitals and 1 secondary care hospital underwent several instruments including the Mini International Neuropsychiatric Interview—Plus Version 5.0.0 (MINI-Plus 5.0.0), the Korean version of the Neurological Disorders Depression Inventory for Epilepsy (K-NDDI-E), the Korean version of the Liverpool Adverse Event Profile (K-LAEP), and the Quality of Life in Epilepsy-10 (QOLIE-10). Two hundred forty-three patients were enrolled in the study, and 51 (21.0%) patients had GAD by the MINI-Plus 5.0.0. Cronbach's α coefficient for the GAD-7 was 0.924. At a cutoff score of 6, the GAD-7 had a sensitivity of 92.2%, a specificity of 89.1%, a positive predictive value of 69.1%, and a negative predictive value of 97.7%. The GAD-7 score was well correlated with the K-NDDI-E score, the K-LAEP score, and the QOLIE-10 overall and subscale scores. The impact of adverse effects of AEDs on the GAD-7 was less than that on the K-NDDI-E. In conclusion, the GAD-7 is a reliable and valid screening tool for detecting GAD in PWE.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Epilepsy & Behavior - Volume 35, June 2014, Pages 59–63
نویسندگان
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