The relationships among medicine symptom distress, self-efficacy, patient–provider relationship, and medication compliance in patients with epilepsy

The purpose of this study was to investigate the relationships among medicine symptom distress, self-efficacy, patient–provider relationship, and medication compliance in patients with epilepsy. Patients with epilepsy (n = 357) were recruited using convenience sampling from three medical centers in northern Taiwan. Results showed significant differences in relationships between medication compliance and the following factors: gender, employment status, comorbid chronic diseases, self-driving, daily drug dosing frequency, seizure after a missed dose, and self-efficacy. Logistic regression analysis indicated that comorbid chronic disease, self-driving, seizure after a missed dose, and self-efficacy were significantly associated with medication compliance. These data suggest that health care providers of patients with epilepsy pay more attention to treatment of comorbid chronic diseases, the safety issues of self-driving, seizures occurring after missed doses, and awareness of self-efficacy.