کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
3050578 1185956 2009 6 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
A clinical and magnetoencephalography study of MRI-negative startle epilepsy
موضوعات مرتبط
علوم زیستی و بیوفناوری علم عصب شناسی علوم اعصاب رفتاری
پیش نمایش صفحه اول مقاله
A clinical and magnetoencephalography study of MRI-negative startle epilepsy
چکیده انگلیسی

ObjectiveThe goal of this study was to investigate clinical findings, ictal semiology, and results of video/electroencephalography (video/EEG), and magnetoencephalography (MEG) in patients with startle epilepsy and normal brain MRI.MethodsFour patients (mean age 12.5 years) with startle epilepsy were investigated with MRI, video/EEG, and MEG.ResultsEpilepsy diagnosis was established in childhood, and all had spontaneous and reflex seizures. Reflex seizures were triggered by sudden, unexpected sounds and tactile stimuli. The neurological examinations and MRIs were normal. MEG recordings showed focal epileptiform activity. An ictal MEG was obtained in one patient. Source modeling yielded dipole sources in right central frontal region.ConclusionThe present study demonstrates that the origin of epileptiform activity in startle epilepsy can be localized in brain areas associated with supplementary motor seizures, even in patients with normal brain MRI. MEG adds complementary information to the localization of epileptiform activity and can be useful in planning invasive studies in cases evaluated for epilepsy surgery.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Epilepsy & Behavior - Volume 16, Issue 1, September 2009, Pages 166–171
نویسندگان
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