کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
3050969 1185968 2008 4 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Predicting epileptic seizures with a mental simulation task: A prospective study
موضوعات مرتبط
علوم زیستی و بیوفناوری علم عصب شناسی علوم اعصاب رفتاری
پیش نمایش صفحه اول مقاله
Predicting epileptic seizures with a mental simulation task: A prospective study
چکیده انگلیسی

The unpredictability of seizures is one of the most disabling aspects of epilepsy. We assessed the possibility of forecasting seizure onset by means of a behavioral task using mental simulation of biological and nonbiological movements. Four patients with epilepsy were included in a longitudinal study. In two patients with right temporal lobe epilepsy (RTLE), performance of the task changed depending on the epileptic cycle. In the preictal phase, timing precision decreased during simulation of biological movements and increased during simulation of nonbiological movements. In two other patients, the timing precision during simulation of biological movements was chronically decreased. The observed phase dependency of performance in patients with RTLE may indicate changes in brain states hours in advance of seizure onset. We suggest that our paradigm might be a simple and accurate method for the prediction of epileptic seizures. The validity of the approach for different types of epilepsy should be assessed in future studies.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Epilepsy & Behavior - Volume 13, Issue 1, July 2008, Pages 256–259
نویسندگان
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