کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
3051258 | 1185978 | 2007 | 4 صفحه PDF | دانلود رایگان |
Seizure severity is an important aspect of epilepsy. The relationship between seizure severity and quality of life in epilepsy, however, has been incompletely explored. With a data set of 118 women from the baseline phase of a clinical treatment trial, the relationship between seizure severity and aspects of quality of life was evaluated. Two domains of the Quality of Life in Epilepsy-31 (QOLIE-31) correlated highly significantly with seizure severity: Seizure Worry (r = −0.265, P = .004) and Social Functioning (r = −0.280, P = 0.002). Two additional domains were significantly correlated: Overall Quality of Life (r = −0.210, P = 0.023) and Cognitive (r = −0.209, P = 0.024). When the potentially confounding effect of depression, measured by the Beck Depression Inventory, was controlled for, the regression of seizure severity with QOLIE-31 Seizure Worry remained significant (P = 0.006, R2 = 0.153), as did the regression with QOLIE-31 Social Functioning (P = 0.002, R2 = 0.184) and the regression with QOLIE-31 Cognitive (P = 0.037, R2 = 0.30). These findings indicate that severe and potentially injurious seizure behaviors contribute to anxiety and socially avoidant behavior for persons with intractable epilepsy.
Journal: Epilepsy & Behavior - Volume 11, Issue 2, September 2007, Pages 208–211