کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
3051278 1185979 2008 4 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
The prognostic value of long-term ambulatory electroencephalography in antiepileptic drug reduction in adults with learning disability and epilepsy in long-term remission
موضوعات مرتبط
علوم زیستی و بیوفناوری علم عصب شناسی علوم اعصاب رفتاری
پیش نمایش صفحه اول مقاله
The prognostic value of long-term ambulatory electroencephalography in antiepileptic drug reduction in adults with learning disability and epilepsy in long-term remission
چکیده انگلیسی

We determined the additional yield of ambulatory over routine electroencephalography recordings in predicting seizure recurrence after antiepileptic drug (AED) withdrawal in 15 adult patients with various epilepsy syndromes who had been seizure free for at least 3 years (median = 10 years). Eleven of 15 patients (74%) relapsed during or after AED withdrawal. All six patients with epileptiform discharges on ambulatory electroencephalography prior to AED withdrawal relapsed, compared with five of nine patients without epileptiform discharges. Ambulatory electroencephalography significantly increases the yield in detecting epileptiform discharges (n = 6) compared with routine electroencephalography (n = 1). A negative electroencephalographic finding is only a poor predictor of seizure freedom following AED withdrawal. On clinical grounds, our data suggest that patients with epilepsy, learning disability, and other known risk factors (history of abnormal EEGs and frequent seizures, abnormal MRI) are at great risk of seizure relapse during AED taper, irrespective of very long periods of seizure freedom.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Epilepsy & Behavior - Volume 13, Issue 3, October 2008, Pages 474–477
نویسندگان
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