Decreased phosphorylation of delta and epsilon subunits of the acetylcholine receptor coincides with delayed postsynaptic maturation in PKC theta deficient mouse

► PKCθ is required for postnatal activity-dependent synapse elimination. ► PKCθ is required for postnatal maturation of the AChR cluster. ► PKCθ is required to maintain phosphorylation of delta and epsilon AChR subunits. ► PKCθ is located pre- and postsynaptically at the neuromuscular junction.