Lymphome cérébral primitif chez un sujet immunocompétent

Primary cerebral lymphoma is a form of non-Hodgkin lymphoma with a solitary localization in the brain, excepting other localizations involving the central nervous system (spinal cord, eye, meninges). This is a rare cancer but with increasing incidence; approximately 300 new cases are diagnosed annually in France. In the 1980s and 1990s, it was predominantly observed in immunodepressed HIV-positive patients but since the advent of effective antiretroviral treatments, it has essentially been observed in immunocompetent patients. Most patients are older adults, with a median age at diagnosis of 65 years. The diagnosis can be difficult but is essential to establish the appropriate therapeutic strategy. We report a case of primary cerebral lymphoma observed in an immunocompetent women.