کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
3093088 1190529 2008 6 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Multivariate analysis of risk factors of hematoma expansion in spontaneous intracerebral hemorrhage
موضوعات مرتبط
علوم زیستی و بیوفناوری علم عصب شناسی عصب شناسی
پیش نمایش صفحه اول مقاله
Multivariate analysis of risk factors of hematoma expansion in spontaneous intracerebral hemorrhage
چکیده انگلیسی

Back groundWe focused on the cause of hematoma expansion after admission because the volume of hematoma after S-ICH plays a crucial role in the cause of mortality and morbidity.MethodsIn a retrospective review, 51 patients with hematoma expansion of S-ICH were identified among 880 cases of S-ICH treated between 2001 and May 2006. We divided cases into 2 groups according to the time of hematoma expansion. An enlargement of hematoma within 2 weeks after hospitalization was categorized as the acute stage group and after 2 weeks was categorized as the chronic stage group. Spontaneous intracerebral hemorrhage without hematoma expansion group (100 cases) had been consecutively selected as a control group. We analyzed the risk factors of hematoma expansion in patients with S-ICH especially in the acute stage group.ResultsFifty-one of 880 patients had the enlargement of hematoma (5.8%). Forty-three (84%) of 51 cases were acutely developed and 8 cases (16%) were developed chronically. On univariate analysis there were significant differences in BP within the initial 48 hours (P < .0001), GOS (P < .0001), and previously taking anticoagulant agents (P = .0053). Especially the difference in SBP and DBP within 48 hours between groups was 19 (11%) and 13 mm Hg (14%), respectively. The DBP within the initial 24 hours had a meaningful odds ratio (1.06) on logistic regression analysis.ConclusionA reduction of BP by 15% (SBP ≤140 mm Hg, DBP ≤80 mm Hg) is necessary at acute stage in S-ICH.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Surgical Neurology - Volume 69, Issue 1, January 2008, Pages 40–45
نویسندگان
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