کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
3093983 1190550 2006 5 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
The role of diffusion-weighted imaging in the differential diagnosis of intracranial cystic mass lesions: a report of 147 lesions
موضوعات مرتبط
علوم زیستی و بیوفناوری علم عصب شناسی عصب شناسی
پیش نمایش صفحه اول مقاله
The role of diffusion-weighted imaging in the differential diagnosis of intracranial cystic mass lesions: a report of 147 lesions
چکیده انگلیسی

BackgroundThe objective of this study is to evaluate the sensitivity and specificity of DWI in differentiating brain abscesses from other intracranial cystic lesions.MethodsOne hundred fifteen patients with 147 cystic lesions (mean age, 26.4 year) were prospectively studied with DWI on a 1.5-T magnetic resonance imaging. Lesions appearing hyperintense on DWI with the ADC values of lower than 0.9 ± 0.13 × 10−3 mm2/s (mean ± SD) were considered as brain abscess, whereas hypointense lesions on DWI with the ADC values 2.2 ± 0.9 × 10−3 mm2/s were categorized as nonabscess cystic lesions.ResultsNinety-three of 97 brain abscess lesions were hyperintense on DWI, with significantly low (P = .0001) ADC value (0.87 ± 0.05 × 10−3 mm2/s) (mean ± SEM), compared with 48 nonabscess lesions (2.89 ± 0.05 × 10−3 mm2/s). Four of 97 brain abscess lesions in 65 patients were false negative, and 2 of 50 nonabscess lesions in 50 patients were false positive for the diagnosis of brain abscess. The ADC value of the tumor cysts (2.9 ± 0.05 × 10−3 mm2/s) was significantly lower (P = .02) compared with benign cysts and neurocysticercosis (3.2 ± 0.05 × 10−3 mm2/s) among nonabscess group. The sensitivity of DWI for the differentiation of brain abscesses from nonabscesses was 96%; specificity, 96%; positive predictive value, 98%; negative predictive value, 92%; and accuracy of the test, 96%.ConclusionsDiffusion-weighted imaging has high sensitivity and specificity for the differentiation of brain abscess from other nonabscess intracranial cystic lesions.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Surgical Neurology - Volume 66, Issue 3, September 2006, Pages 246–250
نویسندگان
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