کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
3095181 1190903 2015 7 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Risk Factors for Delirium After Spinal Surgery: A Meta-Analysis
ترجمه فارسی عنوان
عوامل خطر برای دلیری پس از جراحی ستون فقرات: یک متاآنالیز
موضوعات مرتبط
علوم زیستی و بیوفناوری علم عصب شناسی عصب شناسی
چکیده انگلیسی

ObjectivePostoperative delirium can occur following various types of surgeries. The specific risk factors for delirium following spinal surgery have not been systematically evaluated. The aim of this study is to conduct a meta-analysis of the risk factors for delirium after spinal surgery.MethodsPubMed, EMBASE, the Cochrane Library, and Science Citation Index were searched from inception to October 2014 for original research studies. Relevant studies on patients with delirium following spinal surgery were included if they identified at least 1 risk factor as being associated with delirium. The Newcastle-Ottawa Scale (NOS) was used for the study quality assessment, and the pooled odds ratios (ORs) were used for determining the risk factors.ResultsSix articles met the inclusion criteria. Twenty-four risk factors in the multivariate analyses and 22 factors in the univariate analyses were significantly associated with delirium following spinal surgery. In the pooled analyses, age >65 years (OR: 6.13; 95% confidence interval [CI]: 5.75, 6.54); female sex (OR: 1.21; 95% CI: 1.15, 1.28); number of medications (mean difference [MD]: 1.36; 95% CI: 0.73, 2.00); low preoperative hematocrit (MD: −1.67; 95% CI: −2.97, −0.38) and albumin (MD: −0.33; 95% CI: −0.53, −0.13); duration of surgery (MD: 35.79; 95% CI: 1.42, 70.16); intraoperative blood loss (MD: 124.44; 95% CI: 100.03, 148.85); low postoperative hematocrit (MD: −2.58; 95% CI: −3.70, −1.46), hemoglobin (MD: −1.10; 95% CI: −1.86, −0.35), and sodium (MD: −2.97; 95% CI: −5.42, −0.51); and postoperative fever (OR: 4.52; 95% CI: 2.94, 6.95) were significantly associated with delirium.ConclusionsSeveral risk factors were consistently associated with delirium following spinal surgery, which can be used to identify high-risk patients. Recognizing these patients is important for physicians to develop preventive strategies to reduce postoperative delirium and its negative consequences.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: World Neurosurgery - Volume 84, Issue 5, November 2015, Pages 1466–1472
نویسندگان
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