کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
3097275 1581486 2011 10 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Cerebral Arteriovenous Malformations: Issues of the Interplay Between Stereotactic Radiosurgery and Endovascular Surgical Therapy
موضوعات مرتبط
علوم زیستی و بیوفناوری علم عصب شناسی عصب شناسی
پیش نمایش صفحه اول مقاله
Cerebral Arteriovenous Malformations: Issues of the Interplay Between Stereotactic Radiosurgery and Endovascular Surgical Therapy
چکیده انگلیسی

Intracranial arteriovenous malformations (AVMs) are congenital lesions frequently diagnosed as a result of hemorrhage or other neurological symptoms. Prevention of such devastating neurological injury has promoted a variety of treatment strategies. The rich history of multimodal therapy in the treatment of AVMs includes microsurgery, endovascular embolization, and stereotactic radiosurgery (SRS). This article reviews the biology and natural history of AVMs, as well as their treatment with both SRS and endovascular neurosurgery. It considers various paradigms and goals of endovascular treatment, along with relevant issues such as the features of an AVM to be targeted. Issues of the interplay between SRS and endovascular neurosurgery include the compartments of an embolized AVM to contain within the radiosurgery plan, the radioprotective and radiosensitizing effects of the embolic agent, the durability of embolization, and the sequencing of embolization with respect to the radiosurgical treatment. Published literature on these topics is sparse, and the flimsiness of the data offers limited guidance.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: World Neurosurgery - Volume 75, Issues 5–6, May–June 2011, Pages 638–647
نویسندگان
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