کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
3097305 1190941 2010 4 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Intradural cranial chordoma
موضوعات مرتبط
علوم زیستی و بیوفناوری علم عصب شناسی عصب شناسی
پیش نمایش صفحه اول مقاله
Intradural cranial chordoma
چکیده انگلیسی

BackgroundIntradural chordomas are rare and have been considered benign owing to the feasibility of complete resection and the display of lesser aggressive biologic behavior than typical chordomas.Case DescriptionWe herein reported 2 cases of intradural cranial chordoma with aggressive biologic behavior. A tumor (anti–Ki-67 monoclonal antibody [MIB-1], 13.9%) in a 59-year-old woman was strongly adherent to the brainstem and involved the basilar artery and its branches. After subtotal removal, the remnant tumor was treated with stereotactic radiotherapy. A tumor (MIB-1, 6.2%) in a 75-year-old woman repeatedly recurred even after initial gross total removal. The recurrent chordomas were treated with γ-knife radiosurgery.ConclusionThe cases presented in this study indicate that intradural chordomas can also be aggressive such as typical chordomas. Long-term follow-ups with a large number of patients with this condition are essential for elucidating the prognosis of intradural chordomas.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: World Neurosurgery - Volume 73, Issue 3, March 2010, Pages 194–197
نویسندگان
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