کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
3164055 1198766 2014 9 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Development and characterization of salivary adenoid cystic carcinoma cell line
ترجمه فارسی عنوان
توسعه و مشخصه سلول های کارسینوم عروق کرونر آدنوئید بزاق
کلمات کلیدی
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی دندانپزشکی، جراحی دهان و پزشکی
چکیده انگلیسی

SummaryObjectiveTo develop in vitro adenoid cystic carcinoma cell line as a surrogate for functional studies.Materials and methodsCells obtained from a primary ACC of the base of tongue were cultivated in vitro and immortalized with h-TERT. Morphologic, cytogenetic and functional studies were performed.ResultsTumor cells were verified by positive reactions to keratin and smooth muscle actin and phenotypic cellular and nuclear features. In-vitro cell growth and colony formation assay supported their tumor nature.ConclusionWe authenticated an ACC cell line with hybrid epithelial–myoepithelial feature as a resource for functional experimentation.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Oral Oncology - Volume 50, Issue 10, October 2014, Pages 991–999
نویسندگان
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