کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
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3165373 | 1198832 | 2009 | 5 صفحه PDF | دانلود رایگان |
SummaryThe aim of this study was to investigate whether the recurrence interval influenced survival rate of patients with relapse of oral squamous cell carcinoma (OSCC).From 1992 to 2006, a total of 773 patients with OSCC treated at the Department of Oral and Maxillofacial Plastic Surgery of the Ruhr-University Bochum were reviewed. Statistical analysis included descriptive statistics, Kaplan–Meier survival analyses, receiver operating characteristic, the Youden-Index and analysis using the log-rank test and Cox-regression.The overall recurrence rate was 23.9%. Local recurrence was more common (64.9%) than locoregional recurrence (25.1%). Patients with relapse more than 18 months after completion of their primary treatment had significantly improved survival rates compared with those who relapsed within 18 months of initial treatment (20.5% vs 42.3%). A significant difference was noted in the survival rate between patients with local and locoregional recurrence (37.5% vs 21.5%). Overall survival rate after salvage was 31.9%.The interval from initial treatment to recurrence is an independent prognostic factor for OSCC patients. Patients with a recurrence interval of ⩽18 months had a statistically significant higher probability of death than those with a recurrence interval >18 months. This information can help inform salvage treatment strategies and provide a classification of early and late recurrences.
Journal: Oral Oncology - Volume 45, Issue 8, August 2009, Pages 687–691