کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
3165472 1198836 2009 6 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Squamous cell carcinoma of the gingivobuccal complex: Predictors of locoregional failure in stage III–IV cancers
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی دندانپزشکی، جراحی دهان و پزشکی
پیش نمایش صفحه اول مقاله
Squamous cell carcinoma of the gingivobuccal complex: Predictors of locoregional failure in stage III–IV cancers
چکیده انگلیسی

SummaryThe purpose of our study was to analyze the indicators of loco-regional failure in a large cohort of patients with gingivobuccal complex tumors treated at a single institution.A retrospective review of 2275 patients diagnosed with tumors of the gingivobuccal complex was conducted from January 1997 to December 1999; 642 patients who fulfilled our inclusion criteria were analyzed. A univariate analysis, multivariate analysis, and disease-free survival are reported.During a median follow up of 2.51 years, there were 228 (35.5%) recurrences with a median post-recurrence survival of 2.7 months. The incidence of occult neck metastasis was 29%. The 2- and 5-year DFS rates were 63.8% and 53.3%, respectively. On multivariate analysis, tumor depth and metastatic lymphadenopathy were found to be independent prognostic factors for disease-free survival.Advanced gingivobuccal cancers fail loco-regionally. Cervical metastasis and tumor depth influence disease-free survival. Elective neck dissection due to a high incidence of occult neck disease is recommended.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Oral Oncology - Volume 45, Issue 2, February 2009, Pages 135–140
نویسندگان
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