کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
3165563 1198840 2007 4 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Oral tongue cancer in young patients: A matched analysis
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی دندانپزشکی، جراحی دهان و پزشکی
پیش نمایش صفحه اول مقاله
Oral tongue cancer in young patients: A matched analysis
چکیده انگلیسی

SummaryPrevious studies on squamous cell carcinoma of the tongue have reported conflicting results with respect to age and prognosis. The aim of this study is to elucidate if any differences in outcome exist between patients younger and older than 40 years. A case-control study was performed. Patients recorded in the head and neck cancer registry of Milano-Bicocca School of Medicine between January 1981 and December 1998 were reviewed. Cases were patients with squamous cell carcinoma of the tongue aged 40 years or less. Controls were patients older than 40 who were matched to cases for diagnosis, sex and TNM classification. Two controls were matched for each case, thus forty-six cases and 92 controls were selected. The frequency of recurrences was found to be significantly higher in younger patients. The survival analysis further supports this conclusion (log-rank test, p = 0.002). The number of cancer-related deaths in patients younger and older than 40 years were 23 (50%) and 31 (34%), respectively (p = 0.10). A statistical significant difference emerged when the number of deaths was compared using survival curves (log-rank test, p = 0.05). In conclusion, in patients with squamous cell carcinoma of the tongue, young age is an independent predictor of worse survival.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Oral Oncology - Volume 43, Issue 9, October 2007, Pages 894–897
نویسندگان
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