Porównanie skuteczności ogłuszania mysiego modelu zwierzęcego w oparciu o protokoły wykorzystujÄ ce leki ototoksyczne

Variable outcomes in deafening mouse animal model implies the necessity of hearing evaluation every time prior to the pathophysiological as well as molecular studies. Mice exposed to severe oto- and nephrotoxic insult do not recover after anesthetic drug administration, thus harvesting inner ear tissues especially as the source of RNA should be performed immediately after ABR recordings.