کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
3171220 | 1199852 | 2010 | 5 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
ZwÄżenie podgÅoÅniowe w ziarniniakowatoÅci Wegenera - problem diagnostyczny i terapeutyczny
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موضوعات مرتبط
علوم پزشکی و سلامت
پزشکی و دندانپزشکی
دندانپزشکی، جراحی دهان و پزشکی
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: ZwÄżenie podgÅoÅniowe w ziarniniakowatoÅci Wegenera - problem diagnostyczny i terapeutyczny ZwÄżenie podgÅoÅniowe w ziarniniakowatoÅci Wegenera - problem diagnostyczny i terapeutyczny](/preview/png/3171220.png)
چکیده انگلیسی
Wegener's granulomatosis (WG) is a disease caused by necrotising vasculitis of small and middle blood vessels of upper and lower respiratory tract and kidneys of unknown etiology. ENT symptoms develop in more than 90% of patients and tracheobronchial involvement occurs in about 20% of patients, most often as a subglottic stenosis. Subglottic stenosis occurs usually as a late complication of disease, but sometimes it may be an early isolated symptom. It is usually irregular, no longer than 2-4 cm and affects mucosa and submucosa but sometimes also cartilage. The diagnosis is based on clinical symptoms, X-ray of the chest, urine analysis, c-ANCA detection and histological examination of the granulation from the stenosis. The main treatment of subglottic stenosis in WG is a causal immunosuppressive treatment, however an equally important is a preservation of respiratory tract passage, because a dominant symptom in this form of WG is problem with breathing or even dyspnoea. In this publication basing on literature review different methods of treatment of laryngotracheal stenosis and its importance in WG are described and discussed. In literature presently less invasive operations are recommended. The treatment of choice is endoscopic treatment with repeated dilatations and injections of steroid into the stenosis. In big stenosis in immunologically active disease patient sometimes requires tracheotomy and after remission of disease and maturation of the subglottic scar laryngotracheal resection can be considered.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Otolaryngologia Polska - Volume 64, Issue 1, JanuaryâFebruary 2010, Pages 15-19
Journal: Otolaryngologia Polska - Volume 64, Issue 1, JanuaryâFebruary 2010, Pages 15-19
نویسندگان
MaÅgorzata Wierzbicka, Wojciech GawÄcki, Tomasz Pastusiak, Witold Szyfter,