Występowanie i rola aktywnej infekcji wirusem brodawczaka ludzkiego (HPV) w rakach płaskonabłonkowych głowy i szyi

There was no HPV DNA detected in any case, which may indicate the lower HPV prevalence in polish population than in Western Europe and US and smoking and drinking associated carcinogenesis. The p16 expression has been found in 8% of the patients and supplementary (GP)5+/6+ PCR did not detect the presence of HPV DNA. Thus, the p16 immunostaining is of limited use as a sole method of HPV detection and needs to be complemented by other techniques.