کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
31832 44842 2011 10 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Application and engineering of fatty acid biosynthesis in Escherichia coli for advanced fuels and chemicals
موضوعات مرتبط
مهندسی و علوم پایه مهندسی شیمی بیو مهندسی (مهندسی زیستی)
پیش نمایش صفحه اول مقاله
Application and engineering of fatty acid biosynthesis in Escherichia coli for advanced fuels and chemicals
چکیده انگلیسی

Research towards the commercialization of fungible biofuels has received a great deal of recent interest and investment. To this end the microbial production of fatty acid-derived fuels from sustainable feedstocks is emerging as a viable option with rapid advances from both industry and academia. The manipulation of the fatty acid biosynthesis pathway, especially in Escherichia coli, has been widely studied and several approaches that increase fatty acid production have been identified. However, further advances will be required for the economic large-scale production of fatty acid-derived biofuels. Here we present an overview of fatty acid biosynthesis and its regulation in E. coli from a metabolic engineering viewpoint and offer potential approaches and considerations for the microbial overproduction of custom designed fatty acids for use as biofuels or in the manufacture of oleochemicals.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Metabolic Engineering - Volume 13, Issue 1, January 2011, Pages 28–37
نویسندگان
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