کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
321874 539856 2011 5 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Emotional processing as a predictor of symptom change: An acute tryptophan depletion study in depressed patients
موضوعات مرتبط
علوم زیستی و بیوفناوری علم عصب شناسی روانپزشکی بیولوژیکی
پیش نمایش صفحه اول مقاله
Emotional processing as a predictor of symptom change: An acute tryptophan depletion study in depressed patients
چکیده انگلیسی

Acute tryptophan depletion (ATD) in currently depressed patients has no immediate effect on symptoms, but leads to transient symptom improvement or worsening the next day. In view of recent findings concerning the cognitive effects of serotonin manipulations, we used ATD in fourteen depressed patients to investigate whether cognitive effects following ATD predict symptom changes. We found that symptom improvement 24 h after ATD was associated with an improved recall of positive words and with less attentional bias and recall of negative words, 5 h after ATD. These results indicate that serotonergic alterations affect emotional processing which may subsequently lead to symptom changes.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: European Neuropsychopharmacology - Volume 21, Issue 5, May 2011, Pages 379–383
نویسندگان
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