کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
321874 | 539856 | 2011 | 5 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Emotional processing as a predictor of symptom change: An acute tryptophan depletion study in depressed patients
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کلمات کلیدی
موضوعات مرتبط
علوم زیستی و بیوفناوری
علم عصب شناسی
روانپزشکی بیولوژیکی
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چکیده انگلیسی
Acute tryptophan depletion (ATD) in currently depressed patients has no immediate effect on symptoms, but leads to transient symptom improvement or worsening the next day. In view of recent findings concerning the cognitive effects of serotonin manipulations, we used ATD in fourteen depressed patients to investigate whether cognitive effects following ATD predict symptom changes. We found that symptom improvement 24 h after ATD was associated with an improved recall of positive words and with less attentional bias and recall of negative words, 5 h after ATD. These results indicate that serotonergic alterations affect emotional processing which may subsequently lead to symptom changes.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: European Neuropsychopharmacology - Volume 21, Issue 5, May 2011, Pages 379–383
Journal: European Neuropsychopharmacology - Volume 21, Issue 5, May 2011, Pages 379–383
نویسندگان
Linda Booij, A.J. Willem Van der Does,