کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
3256936 1207377 2013 7 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
GLP-1 agonists in type 1 diabetes
موضوعات مرتبط
علوم زیستی و بیوفناوری ایمنی شناسی و میکروب شناسی ایمونولوژی
پیش نمایش صفحه اول مقاله
GLP-1 agonists in type 1 diabetes
چکیده انگلیسی

Despite years of research in the field of type 1 diabetes, patients with the disease remain without a therapeutic agent that can alter the underlying immune response in a clinically beneficial way. Glucagon-like peptide 1 agonist therapies have shown some promising effects in terms of positively affecting overall beta cell health and increasing beta cell mass, primarily in mouse models. The three agents of this class currently available for patients with type 2 diabetes have shown beneficial clinical effects on glucose control in this patient population.The purpose of this article is to review the preclinical and clinical data of these agents to date with a focus on the potential immunological and clinical benefits these drugs may have on patients with type 1 diabetes.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Clinical Immunology - Volume 149, Issue 3, Part A, December 2013, Pages 317–323
نویسندگان
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