کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
3277753 1208634 2006 13 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Oily fish reduces plasma triacylglycerols: a primary prevention study in overweight men and women
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی غدد درون ریز، دیابت و متابولیسم
پیش نمایش صفحه اول مقاله
Oily fish reduces plasma triacylglycerols: a primary prevention study in overweight men and women
چکیده انگلیسی

ObjectivePrevious studies have demonstrated benefits of high-dose long-chain ω-3 polyunsaturated fatty acid (LC ω-3 PUFA) supplements on metabolic risk. Effects of increased dietary ω-3 PUFA, via oily fish and/or plant-derived ω-3 PUFAs, are less clear and may be modulated by the ω-6:ω-3 PUFA of the habitual diet. This study examined the effect on cardiovascular disease risk markers of reducing dietary ω-6:ω-3 PUFA by changes in linoleic acid:α-linolenic acid (LA:LNA) and/or increasing LC ω-3 PUFA. It tested whether decreases in LA:LNA modulate effects of LC ω-3 PUFA.MethodsOne hundred forty-two subjects, recruited to a 24-wk randomized study, were assigned to a control group or one of four interventions. Intervention groups received two portions of oily fish (4.5 g eicosapentaenoic acid + docosahexanoic acid) or white fish (0.7 g eicosapentaenoic acid + docosahexanoic acid) per week, and replaced habitual household fats with ones high in sunflower (high LA:LNA) or rapeseed (low LA:LNA) oil.ResultsModest dietary manipulations of ω-6 and ω-3 PUFAs resulted in significant group × time interactions for serum triacylglycerols (TAGs; P = 0.05); at 24 wk the control and two oily fish groups showed lower TAG than did the white fish/sunflower group (P = 0.05). Reductions in TAG, associated with increased oily fish intakes, were maximized when combined with lower dietary LA:LNA. There were no significant changes in several other cardiovascular disease risk markers.ConclusionsTwo portions of oily fish per week led to significant reductions in TAG relative to consumption of two portions of white fish per week. Changes in TAG were maximized when combined with lower LA:LNA.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Nutrition - Volume 22, Issue 10, October 2006, Pages 1012–1024
نویسندگان
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