کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
3285733 | 1209239 | 2006 | 11 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Natural History of Patients Hospitalized for Management of Cirrhotic Ascites
دانلود مقاله + سفارش ترجمه
دانلود مقاله ISI انگلیسی
رایگان برای ایرانیان
کلمات کلیدی
GGTSBPHRSHCC - HCCγ-glutamyltransferase - γ-گلوتامیل ترانسفرازRefractory ascites - آسیت نسوزhepatic encephalopathy - آنسفالوپاتی کبدیRelative risk - خطر نسبیhepatorenal syndrome - سندرم هپاترونالtransjugular intrahepatic portosystemic shunt - شنت پورتوژئوس داخل صفاقی transjugularconfidence interval - فاصله اطمینانModel for End-Stage Liver Disease - مدل بیماری کبد مرحله پایانیhazard ratio - نسبت خطرTIPS - نکاتspontaneous bacterial peritonitis - پریتونیت باکتریایی خودبه خودیHepatocellular carcinoma - کارسینوم هپاتوسلولار(کارسینوم سلولهای استخوانی)MELD - گزارش
موضوعات مرتبط
علوم پزشکی و سلامت
پزشکی و دندانپزشکی
بیماریهای گوارشی
پیش نمایش صفحه اول مقاله
چکیده انگلیسی
Background & Aims: Since the International Ascites Club published the diagnostic criteria of refractory ascites (RA) and hepatorenal syndrome (HRS), there have been few studies assessing the natural history of ascites. The aims of this study were to define the natural history of cirrhotic ascites and to identify prognostic factors for dilutional hyponatremia (DH), RA, HRS, and survival. Methods: Two hundred sixty-three consecutive cirrhotic patients were followed for 40.9 ± 2.6 months after their first significant ascites. Results: During follow-up 74 (28.1%) patients developed DH, 30 (11.4%) RA (diuretic-resistant in 2 cases and diuretic-intractable because of the development of diuretic-induced complications in 28 cases), and 20 (7.6%) HRS (type 1, 7; type 2, 13). The 5-year probability of DH, RA, and HRS development was 37.1%, 11.4%, and 11.4%, respectively. The probability of survival at 1 and 5 years was 85% and 56.5%, respectively. The independent predictors for survival were baseline age, baseline Child-Pugh score, and DH development. The 1-year probability of survival after developing DH, RA, and type 2 HRS was 25.6%, 31.6%, and 38.5%, respectively. In contrast, the mean survival was only 7 ± 2 days in those patients developing type 1 HRS. Conclusions: (1) The survival of cirrhotic patients with first episode of ascites is relatively high, and it is mainly influenced by age and Child-Pugh score at the time of ascites decompensation, as well as by DH development. (2) The probability of RA and HRS development is relatively low, but they are associated with a poor prognosis.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Clinical Gastroenterology and Hepatology - Volume 4, Issue 11, November 2006, Pages 1385-1394, 1394.e1
Journal: Clinical Gastroenterology and Hepatology - Volume 4, Issue 11, November 2006, Pages 1385-1394, 1394.e1
نویسندگان
Ramon Planas, Silvia Montoliu, Belen Ballesté, Monica Rivera, Mireia Miquel, Helena Masnou, Jose Antonio Galeras, MarÃa D. Giménez, Justiniano Santos, Isabel Cirera, Rosa MarÃa Morillas, Susanna Coll, Ricard Solà ,