کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
3317383 | 1211563 | 2011 | 14 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Molecular Imaging of Cell Therapy for Gastroenterologic Applications
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کلمات کلیدی
SPECT - برشنگاری رایانهای تک فوتونی، مقطع نگاری رایانهای تک فوتونی، توموگرافی رایانهای تک فوتونی، اسپکتBioluminescence - بیولومینسانسMagnetic resonance imaging - تصویربرداری رزونانس مغناطیسیMolecular imaging - تصویربرداری مولکولیRadionuclides - رادیونوکلئید Stem cells - سلول های بنیادیPET - پتNuclear medicine - پزشکی هستهایReporter genes - ژن خبرنگار
موضوعات مرتبط
علوم پزشکی و سلامت
پزشکی و دندانپزشکی
بیماریهای گوارشی
پیش نمایش صفحه اول مقاله
چکیده انگلیسی
Stem cell therapy has appeared as a possible therapeutic alternative for numerous diseases. Furthermore, cancer stem cells are a focus of significant interest as they may allow for a better understanding of the genesis of different malignancies. The ultimate goal of stem cell therapeutics is to ensure the viability and functionality of the transplanted cells. Similarly, the ultimate goal of understanding cancer stem cells is to understand how they behave in the living subject. Until recently, the efficacy of stem cell therapies has been assessed by overall organ function recovery. Understanding the behavior and biology of stem cells directly in the living subject can also lead to therapy optimization. Thus, there is a critical need for reliable and accurate methods to understand stem cell biology in vivo. Recent advances in both imaging and molecular biology have enabled transplanted stem cells to be successfully monitored in the living subject. The use of molecular imaging modalities has the capability to answer these questions and may one day be translated to patients. In this review, we will discuss the potential imaging strategies and how they can be utilized, depending on the questions that need to be answered.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Pancreatology - Volume 11, Issue 4, August 2011, Pages 414-427
Journal: Pancreatology - Volume 11, Issue 4, August 2011, Pages 414-427
نویسندگان
Vanessa M. Dimayuga, Martin Rodriguez-Porcel,