کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
3318043 | 1211579 | 2010 | 6 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Fatty Acid Composition of Plasma Lipid Classes in Chronic Alcoholic Pancreatitis
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کلمات کلیدی
موضوعات مرتبط
علوم پزشکی و سلامت
پزشکی و دندانپزشکی
بیماریهای گوارشی
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چکیده انگلیسی
Background/Aims: Supplementation of n-3 long-chain polyunsaturated fatty acids (LCPUFA) is considered as adjuvant therapy in acute pancreatitis. We investigated plasma fatty acid status in chronic pancreatitis (CP). Methods: Patients with alcoholic CP (n = 56, gender: 33/23 male/female, age: 60.0 [14.0] years (median [IQR]), who reported giving up alcohol consumption several years ago and 51 control subjects were included into the study. The fatty acid composition of plasma phospholipids (PL), triacylglycerols (TG) and sterol esters (STE) was analyzed. Results: The sum of monounsaturated fatty acids was significantly higher in patients with CP than in controls (PL; 12.83 [3.35] vs. 12.20 [1.95], TG; 40.51 [6.02] vs. 37.52 [5.80], STE; 20.58 [7.22] vs. 17.54 [3.48], CP vs. control, % weight/weight, median [IQR], p < 0.05). Values of arachidonic acid were significantly lower in patients with CPthan in controls (PL; 10.57 [3.56] vs. 11.66 [3.25], STE; 8.14 [2.63] vs. 9.24 [2.86], p ! 0.05). Values of eicosapentaenoic acid and docosahexaenoic acid did not differ and there was no difference in the ratio of n-3 to n-6 LCPUFA. Conclusion: Our present data do not furnish evidence for the supplementation of n-3 LCPUFA to the diet of CP patients in relatively good clinical condition.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Pancreatology - Volume 10, Issue 5, December 2010, Pages 580-585
Journal: Pancreatology - Volume 10, Issue 5, December 2010, Pages 580-585
نویسندگان
Tamas Marosvolgyi, Gabor Horvath, Aniko Dittrich, Judit Cseh, Zsuzsanna Lelovics, Eva Szabo, Tamas Decsi, Maria Figler,